Microextraction Techniques for Forensic Drug Analysis in Saliva
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چکیده
Forensic drug analysis involves qualitative and quantitative analysis of drugs of abuse and their metabolites in various complex biological matrices such as biological fluids and seized materials. Drugs of abuse such as opioids, cannabinoids, cocaine, amphetamines, hallucinogens and benzodiazepines are generally analyzed in biological fluids e.g. urine and plasma. While urine is efficient for investigation of metabolites, plasma reflects total concentration of drug (bound and unbound) [1]. In recent times, saliva has emerged as an alternative biological matrix for screening and determination of drugs of abuse. Main advantages of saliva drug testing are,
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